Publications

Structural basis of ligand recognition in 5-HT3 receptors

Divya Kesters, Andrew J. Thompson, Marijke Brams, Rene´ van Elk, Radovan Spurny, Matthis Geitmann, Jose M. Villalgordo, Albert Guskov, U. Helena Danielson, Sarah C. R. Lummis, August B. Smit and Chris Ulens (2013), EMBO reports, Jan 3;14(1) Abstract The 5-HT3 receptor is a pentameric serotonin-gated ion channel,... [...]

Aliskiren displays long-lasting interactions with human renin

Gossas T, Vrang L, Henderson I, Sedig S, Sahlberg C, Lindström E, Danielson U. H. (2012) N-S Arch. Pharmaco. 385(2);219-24 Abstract Aliskiren is a selective renin inhibitor recently approved for use in hypertension. Efficacy duration appears longer than what would be expected based on its circulating half-life.... [...]