Aliskiren displays long-lasting interactions with human renin

Gossas T, Vrang L, Henderson I, Sedig S, Sahlberg C, Lindström E, Danielson UH, N-S Arch Pharamacol, 2012, 385:219-224.

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Events


Beactica and Almac Discovery announce their first fragment-based drug discovery agreement

Beactica, the leading Swedish fragment-based drug discovery company, today announced that it has entered into an agreement with Almac Discovery Ltd., an independent member of the Almac Group Ltd. Under the agreement, Beactica will use its proprietary drug discovery platform, Sprint™, to identify high-quality fragment hits against a number of undisclosed targets of therapeutic interest to Almac Discovery.

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Events


Beactica celebrated as Sweden’s fastest growing young biotech at Deloitte’s “Technology Rising Star” awards

Beactica, the leading Swedish fragment-based drug discovery company spun out from Uppsala University in 2006, was recognised as the fastest growing young biotech in Sweden by management consultants Deloitte at the “Technology Rising Stars” prize giving ceremony in Stockholm this week.

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Events


13-14 March 2012

Beactica presents at Select Bioscience’s Discovery Chemistry Congress in Munich, Germany.

Events


17-18 November 2011

Beactica CSO presents at 2011 Nordic Biacore and MicroCal users’ meeting in Copenhagen, Denmark.

Events


Beactica nominated as “Technology Rising Star” by Deloitte

Beactica, the leading Swedish fragment-based drug discovery company spun out from Uppsala University announces that it is amongst 25 companies nominated as “Technology Rising Stars” by management consultants Deloitte.

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Events


13-15 November 2011

Beactica participates in Protein Structure Determination in Industry 2011 (PSDI) in Stenungsbaden, Sweden.

Events


31 Oct-2 Nov 2011

Beactica participates in BIO-Europe 2011 in Duesseldorf, Germany.

Events


12-15 November 2011

Beactica presents at Developments in Protein Interaction Analysis (DiPIA) in Boston, MA.

Events


8-9 June 2011

Beactica participates in the 12th Annual Drug Discovery Leaders Summit in Zurich, Switzerland.

Events


A surface plasmon resonance-based biosensor with full-length BACE1 in a reconstituted membrane

Christopeit T, Stenberg G, Gossas T, Nyström S, Baraznenok V, Lindström E, Danielson UH. Anal Biochem, 2011, 414:14-22.

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Events


6-8 June 2011

Beactica presents at CHI’s 9th Annual Next-Gen Kinase Inhibitors in Cambridge, MA.

Events


25 May 2011, 11:00 AM EDT

Beactica CSO holds webinar hosted by Biacore Life Sciences, GE Healthcare. Register free by clicking here.

Events


Beactica announces fragment-based drug discovery agreement

Beactica, the leading Swedish fragment-based drug discovery company, today announced that it has entered into an agreement with Janssen Research & Development, a division of Janssen Pharmaceutica NV. Under the agreement, Beactica will use its proprietary drug discovery platform, Sprint™, to generate small-molecule lead compounds against undisclosed targets of therapeutic interest to Janssen. Financial terms of the agreement were not disclosed.

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Events


Experimental validation of a fragment library for lead discovery using SPR biosensor technology

Elinder M, Geitmann M, Gossas T, Källblad P, Winquist J, Nordström H, Hämäläinen M, Danielson UH. J Biomol Screen, 2011, 16:15-25.

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Events


Beactica awarded €0.7 million from EU for pioneering influenza research

Beactica, the leading Swedish fragment-based drug discovery company, today announced that it has received a grant of up to €700 000 from the EU 7th Framework Programme to support the Company’s pioneering work in the area of influenza.

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Events


12-14 April 2011

Beactica presents at CHI’s 6th Annual Drug Discovery Chemistry conference in San Diego, CA.

Events


Beactica scientists describe strategies for fragment-based drug discovery in two publications in Journal of Medicinal Chemistry

Beactica, the leading Swedish fragment-based drug discovery company, today announced the publication of two key papers based on in-house research in the field-leading Journal of Medicinal Chemistry*. The papers present methodological advances in SPR biosensor-based drug discovery targeting structurally dynamic proteins, a significant challenge for the pharmaceutical industry, that have been implemented in Beactica’s Sprint™ platform.

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Events


Identification of a novel scaffold for allosteric inhibition of wild type and drug resistant HIV-1 reverse transcriptase by fragment library screening

Geitmann M, Elinder M, Seeger C, Brandt P, de Esch IJ, Danielson UH. J Med Chem, 2011, 54:699-708.

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Events


Deconstruction of non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1 for exploration of the optimization landscape of fragments

Brandt P, Geitmann M, Danielson UH. J Med Chem, 2011, 54:709-18.

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Events


Quantification of interactions between drug leads and serum proteins by use of “binding efficiency”

Gustafsson SS, Vrang L, Terelius Y, Danielson UH. Analytical Biochemistry, 2011, 409:163-75.

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Events


Beactica announces the appointment of a new Chairman and a new Member to its Board

Beactica, the leading Swedish fragment-based drug discovery company, today announced that board member Gisela Sitbon will assume the position of Chairman and that Mr Jan Mellberg will join its Board, both effective immediately.

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Events


22-23 March 2011

Beactica Principal Scientist presents at the 10th Annual Target & Tools: Protein Kinases Conference in Berlin, Germany.

Events


Beactica increases its capacity to address complex research challenges with a Biacore 4000

Beactica, the Swedish fragment-based drug discovery company, today announced an important move to address the need for increased data quality and higher capacity in understanding molecular interactions. Growing customer demand for solutions to ever more complex research challenges has led Beactica to invest in the world’s most sophisticated SPR biosensor to date, the Biacore 4000. The instrument will enable Beactica to offer more advanced experimental designs and a deeper interpretation of interaction analysis data so that stronger therapeutic candidates can be developed.

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Events


Beactica scientists reveal novel strategies for discovery of drugs targeting ion channels involved in synaptic signalling

Beactica, the Swedish fragment-based drug discovery company, today announced the publication of three key papers in leading scientific journals*. The papers describe important work towards the discovery of novel drugs targeting Cys-loop ion channel receptors, a significant family of drug targets involved in various neurological diseases, for example epilepsy.

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Events


Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptor α7 ligands.

de Kloe GE, Retra K, Geitmann M, Källblad P, Nahar T, van Elk R, Smit AB, van Muijlwijk-Koezen JE, Leurs R, Irth H, Danielson UH, de Esch IJ. J Med Chem, 2010, 53:7192–7201.

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Events


Interaction kinetic and structural dynamic analysis of ligand binding to acetylcholine-binding protein.

Geitmann M, Retra K, de Kloe GE, Homan E, Smit AB, de Esch IJ, Danielson UH. Biochemistry. 2010, 49:8143-54.

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Events


15-17 November 2010

Beactica participates in BIO-Europe Partnering 2010 in Munich, Germany.

Events


10-13 October 2010

Beactica participates in Fragment-Based Lead Generation 2010 in Philadelphia, PA.

Events


12-16 September 2010

Beactica’s Chief Scientific Officer presents at XXth National Meeting on Medicinal Chemistry in Padova, Italy.

Events


9-10 June 2010

Beactica’s Chief Executive Officer speaks at The 11th Annual Drug Discovery Leaders Summit in Montreaux, Switzerland.

Events


27-28 May 2010

Beactica Senior Scientist presents at The 5th Annual Protein Kinases in Drug Discovery Conference in Boston, USA.

Events


27-29 April 2010

Beactica Senior Scientist presents at Drug Discovery Chemistry 2010 in San Diego, USA.

Events


22-25 March 2010

Beactica’s Chief Scientific Officer presents at The International Workshop on New Approaches in Drug Design & Discovery in Schloss Rauischholzhausen, Germany.

Events


27-28 May 2010

Beactica Senior Scientist presents at The 5th Annual Protein Kinases in Drug Discovery Conference in Boston, USA.

Events


2-4 November 2009

Beactica participates in BIO-Europe Partnering 2009 in Vienna, Austria.

Events


21-23 September 2009

Beactica presents a poster at Fragment-Based Lead Discovery 2009 in York, UK.

Events


19-24 July 2009

Beactica’s Chief Scientific Officer presents at the Gordon Research Conference on Computer-Aided Drug Design in Tilton, USA.

Events


26 June 2009

Beactica’s Chief Scientific Officer presents at Fragment-Based Lead Discovery Summit in London, UK.

Events


15-16 June 2009

Beactica’s Chief Executive Officer presents at 10th Annual Drug Discovery Leaders Summit in Montreaux, Switzerland.

Events


3-8 May 2009

Beactica’s Chief Scientific Officer presents at Trends in Drug Research, the 27th Noordwijkerhout-Camerino-Cyprus Conference in Noordwijkerhout, The Netherlands.

Events


6-8 April 2009

Beactica’s Chief Executive Officer presents at Drug Discovery Chemistry 2009 in San Diego, USA.

Events


Effect of the protonation state of the titratable residues on the inhibitor affinity to BACE-1.

Domínguez JL, Christopeit T, Villaverde MC, Gossas T, Otero JM, Nyström S, Baraznenok V, Lindström E, Danielson UH, Sussman F. Biochemistry. 2010, 49:7255-63.

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Events


4-5 March 2009

Beactica participates in Fragments 2009 in Alderley Park, UK.

Events


24-25 February 2009

Beactica Senior Scientist presents at BIOPROSP 2009 in Tromsoe, Norway.

Events


8 October 2008

Beactica’s Chief Scientific Officer is part of expert commentary panel on the Nobel Committee’s press conference in conjunction with the announcement of the 2008 Nobel Prize in Chemistry.

Events


23-24 September 2008

Beactica’s Chief Executive Officer presents at Drug Discovery 2008 in Bournemouth, UK.

Events


17-20 June 2008

Beactica participates in Business Forum Partnering at BIO 2008 in San Diego, USA.

Events


10-11 Juni 2008

Beactica participates in Label Free Technologies in Drug Discovery in Dresden, Germany.

Events


27 May 2008

Beactica’s Chief Executive Officer presents at Drug Discovery Chemistry 2008 – Tools, Targets & Therapies in La Jolla, USA.

Events